There are several Nav1.1 antibodies available from commercial sources. All of the following information compares the antibody properties against the protein sequence for human full-length Nav1.1 based on Accession Number P35498.
Abcam
- Type: polyclonal
- Reactivity: rabbit anti-rat Nav1.1
- AA sequence: EEQKKYYNAMKKLGSKKP
- Position:
- raised against: 1502-1519 of rat Nav1.1 (P04774)
- human Nav1.1[full]: 1502-1519 of human Nav1.1 (100 % match)
- mouse Nav1.1[full]: not yet checked
- Topology: L3
- Catalog number: AB24820
- Other: WARNING - likely cross reactivity with human Nav1.9 based on 100 % sequence match (NM_014139), other paralogs not checked
AbD Serotec
- does not carry a Nav1.1 antibody
Alomone Labs
- Type: polyclonal
- Reactivity: rabbit anti-rat Nav1.1
- AA sequence: TASEHSREPSAAGRLSD
- Position:
- raised against: 465-481 of rat Nav1.1 (P04774)
- mouse (not checked yet)
- human (not checked yet)
- Topology: L1
- Catalog number: ASC-001
Life Span Biosciences
- Type: polyclonal
- Reactivity: rabbit anti-rat/mouse/human
- AA sequence: n/a
- Position: n/a
- Topology: n/a
- Catalog number: LS-C143
- Other: No longer available.
Millipore
Nav1.1 only:
- Type: polyclonal
- Reactivity: rabbit anti-rat Nav1.1
- AA sequence: TASEHSREPSAAGRLSD
- Position:
- raised against: 465-481 of rat Nav1.1 (P04774)
- mouse not checked, yet
- human not checked, yet
- Topology: L1
- Catalog number: AB5204
- Other: technically identical to Alomone antibody
Pan (all Navs):
- Type: polyclonal
- Reactivity: rabbit anti-rat Nav1.1-9 (suppposedly all Nav1.x isoforms)
- AA sequence: TEEQKKYYNAMKKLGSKK
- Position:
- raised against: 1501-1518 of rat Nav1.1 (P04774)
- human orthologs not checked, yet
- rat paralogs not checked, yet
- Topology: L3
- Catalog number: AB5210
NeuroMab
- Type: monoclonal
- Reactivity: mouse anti-rat Nav1.1
- AA sequence: HLLKRTVKQASFTYNKNKLKGGANLLVKEDMIIDRINENSITEKTDLTMSTAACPPSYDR
VTKPIVEKHEQEGKDEKAKGK
- Position:
- raised against: 1929-2009 of rat Nav1.1 (P04774)
- mouse: 98% identity (80/81 amino acids identical)
- human: 97% identity (79/81 amino acids identical)
- Topology: very end of C-terminus
- Catalog number: K74_71
Sigma
- Type: ?